Amino acid derivatives are substances formed by the combination of amino acids through a series of reactions. Amino acid derivatives have been widely used in the field of anticancer drugs. Amino acid carrier has good biocompatibility and affinity. Using amino acid or oligopeptide as carrier and introducing it into drug molecules to modify the structure of anti-tumor drugs can improve the targeting of tumor cells, enhance drug solubility and alleviate the toxicity of drugs to normal cells.